Authors & Affiliations

Pryanichnikov A.A.1,3, Simakov A.S.1, Belikhin M.A.1,3, Degtyarev I.I.2, Novoskoltsev F.N.2, Altukhova E.V.2, Altukhov Yu.V.2, Sinyukov R.Yu.2
1 Physical-Technical Center of P.N. Lebedev Physical Institute of the Russian Academy of Sciences, Protvino, Russia
2 Institute for High Energy Physics named by A.A. Logunov of NRC “Kurchatov Institute”, Protvino, Russia
3 Lomonosov Moscow State University, Moscow, Russia

Pryanichnikov A.A. – Research Engineer, PhD student, Physical-Technical Center of P.N. Lebedev Physical Institute of the Russian Academy of Sciences, Lomonosov Moscow State University. Contacts: 2/110, Akademicheskiy proezd, Protvino, Moscow region, Russia, 142281. Tel.: +7(916)080-68-51; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it..
Simakov A.S. – Engineer, Physical-Technical Center of P.N. Lebedev Physical Institute of the Russian Academy of Sciences.
Belikhin M.A. – Research Engineer, PhD student, Physical-Technical Center of P.N. Lebedev Physical Institute of the Russian Academy of Sciences, Lomonosov Moscow State University.
Degtyarev I.I. – Senior Researcher, Cand. Sci. (Phys.-Math.), Institute for High Energy Physics named by A.A. Logunov of NRC “Kurchatov Institute”.
Novoskoltsev F.N. – Senior Researcher, Cand. Sci. (Phys.-Math.), Institute for High Energy Physics named by A.A. Logunov of NRC “Kurchatov Institute”.
Altukhova E.V. – Junior Researcher, Institute for High Energy Physics named by A.A. Logunov of NRC “Kurchatov Institute”.
Altukhov Yu.V. – Junior Researcher, Institute for High Energy Physics named by A.A. Logunov of NRC “Kurchatov Institute”.
Sinyukov R.Yu. – Junior Researcher, Institute for High Energy Physics named by A.A. Logunov of NRC “Kurchatov Institute”.

Abstract

Lately, beams of heavy charged particles, e.g., protons and carbon ions, have found wide application in radiation therapy of oncological diseases owing to the fundamental possibility of qualitative im-provement of the spatial dose distributions when compared to sources of electrons and γ-rays conven-tionally used in radiation therapy, which makes it possible to radically decrease the radiation absorbed dose of the undamaged regions of the tissue adjacent to a tumor. In this paper a results of computer simulation are compared with experimental data for carbon ion carbon ion ranges in homogeneous phantoms using the RTS&T, FLUKA and MCNPX Monte Carlo multi-particle particle and ion transport code systems. Calculations of the main microdosimetric characteristics for cellular structures placed in homogeneous water phantoms are shown: average dose, linear energy transfer (LET), relative biological efficacy (RBE) and biological dose based on the Microbiological Kinetic Model (MKM) within software complex RTS&T. Calculations were made for the beam of 12C6+ ions with the energy of 454 MeV/u. Experimental data were obtained at the Temporary Radiobiological Stand of the U-70 accelerator complex at the Institute of High Energy Physics NRC "Kurchatov Institute", Protvino.

Keywords
radiation transport, Monte Carlo method, radiation therapy, medical accelerators, Bragg peak verification, mathematical modeling, irradiation planning, detection techniques

Article Text (PDF, in Russian)

References

UDC 621.039

Problems of Atomic Science and Technology. Series: Nuclear and Reactor Constants", 2019, issue 2, 2:1